Opioid Adverse Drug Events (ORADES)
Negative Impact On Postoperative Quality Of Life For Patients, Hospital Ratings And Revenue
Opioid Adverse Drug Events (ORADES) can Create a Negative Impact on Postoperative Quality of Life for Patients undergoing Cardiothoracic surgery. They also were found to have a negative effect on Hospital Ratings and Revenues.
80% of patients undergoing invasive surgery experience severe to moderate postoperative pain. While opioids are used in hospitals to manage pain during and after invasive surgical procedures, adverse drug events such as respiratory problems including ventilator use, nausea and vomiting, bowel obstruction, confusion and delirium, dermatitis and others are quite common.
In 2019 Keith B. Allen and colleagues conducted a study to establish the degree to which opioid-related adverse events impact patient quality of life, clinical outcomes and hospital revenues.
They analysed data from 50,525 patients who underwent cardiac valve surgery and 59,633 Medicare beneficiaries who underwent Coronary bypass surgery between April 2016 and March 2017.
Based on the International Classification of Disease (ICD-10) codes linked to Adverse Drug Events, 0.7% = 743 of 110,158 patients had been reprted to have experienced ORADES. Yet the analysis revealed, that up to 32.4 %= 35,658 of 110,158 patients may have experienced adverse drug events.
By comparison of data from patients with and without adverse drug events it was found that opioid-related adverse drug events potentially increased the length of hospital stay per patient by 3.2 days and lowered the mean Medicare revenue for the hospital by $395 per patient, each day.
The average difference in net revenue between the two groups was running between $ 231 and $ 1145.
It can therefore be concluded, that opioid-related adverse drug events following cardiac surgery are underreported and associated with worse clinical outcomes, prolonged hospital stays for patients and a decrease in hospital revenues.
The date of this study provide evidence for the necessity of alternative strategies in postoperative pain management. Changes towards models with less exposure to opioids are very desirable, as they could improve clinical outcomes by reduction of complications and reduction of healthcare costs.
Relate to this article on pain reduction with the Posthorx Support Vest.
Reference: Keith Allen et al.: Opioid-related drug events: incidence and impact in patients undergoing cardiac surgery
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